The Athlete Biological Passport (ABP) offers a longitudinal method to monitor athletes' biological profiles in sport through three modules: steroidal (urine and blood), haematological, and endocrine. These modules track biomarkers over time, with NextGen (ADAMS) applying module-specific criteria and adaptive thresholds to assess samples. Results exceeding these thresholds or those showing unusual patterns trigger atypical or flagged passports. The Athlete Passport Management Unit (APMU), a dedicated unit within certain WADA-accredited laboratories, manages the ABP profiles on behalf of Passport Custodians. This presentation will examine the APMU's critical role in overseeing the ABP process, emphasising the workflow involved in the review and management of profiles across all modules.